Peptides: A Package for Data Mining of Antimicrobial Peptides

Peptides: A Package for Data Mining of Antimicrobial Peptides
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肽:抗菌肽数据挖掘包

DOI:
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发表时间:
2015
期刊:
The R Journal
影响因子:
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通讯作者:
R. Torres
R. Torres
中科院分区:
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文献类型:
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作者:
Daniel Osório;P. Rondón;R. Torres

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抗菌肽(AMP)是一种很有前途的抗生素来源,具有广谱抗菌活性和低耐药发生率。AMP执行其功能的机制取决于来自氨基酸序列的一组可计算的物理化学性质。多肽包是为了快速、方便地计算抗菌肽自身的10个结构特征而设计的,目的是为提高新的氨基酸序列分类和设计的准确性而产生数据。此外,还包括读取和绘制来自GROMACS分子动力学程序包的XVG输出文件的选项。
Antimicrobial peptides (AMP) are a promising source of antibiotics with a broad spectrum activity against bacteria and low incidence of developing resistance. The mechanism by which an AMP executes its function depends on a set of computable physicochemical properties from the amino acid sequence. Peptides package was designed for allowing the quick and easy computation of ten structural characteristics own of the antimicrobial peptides, with the aim of generating data for increase the accuracy in classification and design of new amino acid sequences. Moreover, the options to read and plot XVG output files from GROMACS molecular dynamics package was included.
DOI: 10.1101/gr.361602
发表时间: 2002-10-01
期刊: GENOME RESEARCH
影响因子: 7
作者:
Stajich, JE;Block, D;Birney, E
通讯作者: Birney, E