Patterns of premorbid functioning in first-episode psychosis: initial presentation
Patterns of premorbid functioning in first-episode psychosis: initial presentation
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DOI：
10.1016/s0920-9964(02)00408-5
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发表时间：
2003-07-01
影响因子：
4.5
通讯作者：
Addington, D
中科院分区：
文献类型：
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作者：
Addington, J;van Mastrigt, S;Addington, D
据报道，首发精神病患者的病前功能与不良结局相关。我们评估了一个样本的306名受试者新承认的早期精神病程序的病前功能。使用聚类分析，我们确定了四种模式：稳定-良好，稳定-中等，恶化和差-恶化。结果是，相对于稳定良好组，恶化组和恶化组有更多的阴性症状，社会功能较差，认知功能较差的一些证据。与稳定良好组相比，恶化组的阳性症状增加。这些结果表明，在急性精神病发作之前，那些具有不良的社会和人际功能的人与那些具有较好的病前功能的人相比，在发病前最初表现出增加的社会障碍和阴性症状。(C)2003 Elsevier Science B. V.保留所有权利。
Premorbid functioning in first-episode psychosis has been reported to be associated with poorer outcome. We assessed premorbid functioning in a sample of 306 subjects newly admitted to an early-psychosis program. Using cluster analyses, we identified four patterns: stable-good, stab le-moderate, deteriorating and poor-deteriorating. Results were that relative to the stable-good group, the deteriorating and the poor-deteriorating groups had more negative symptoms, poorer social functioning and some evidence of poorer cognitive functioning. The deteriorating group had increased positive symptoms compared to the stable-good group. These results suggest that prior to the onset of the acute psychosis those who have poor social and interpersonal functioning premorbidly present initially with increased social impairment and negative symptoms compared to those who have better premorbid functioning. (C) 2003 Elsevier Science B.V. All rights reserved.