Effect of Probiotics on the Performance and Intestinal Health of Broiler Chickens Infected with Eimeria tenella.
Effect of Probiotics on the Performance and Intestinal Health of Broiler Chickens Infected with Eimeria tenella.
复制标题
益生菌对感染柔嫩艾美耳球虫的肉鸡生产性能和肠道健康的影响
DOI：
10.3390/vaccines10010097
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发表时间：
2022-01-10
期刊：
影响因子：
7.8
通讯作者：
Yin G
中科院分区：
文献类型：
--
作者：
Mohsin M;Zhang Z;Yin G
球虫病是一种重要的家禽寄生虫病，具有重要的经济意义。由于耐药性的问题，这项研究是为了调查益生菌（植物乳杆菌或L。plantarum）影响每克粪便卵囊数（OPG）、粪便评分、饲料转化率（FCR）、细胞介导的免疫调节效应和体液免疫应答。在不同处理的鸡组中测量血清化学（ALT、AST、LDH和肌酸酐）。检测了感染柔嫩艾美耳球虫（Eimeria tenella，E. tenella）。添加L. 1 × 108 CFU（colony-formingunit，CFU）组的细胞免疫和体液免疫均较对照组增强（p < 0.05）。与对照感染的未用药鸡相比，益生菌还增强了抗氧化酶PepT 1和紧密连接蛋白的性能，并改善了血清化学（AST，ALT和LDH）。然而，在所有处理的鸡组中未观察到CLDN 1表达水平和肌酐的显著差异（p > 0.05）。说明在饲料中添加益生素可以保护鸡抵抗大肠杆菌的侵害。tenella感染
Coccidiosis is an important parasitic disease of poultry with great economic importance. Due to drug resistance issues, the study was conducted to investigate how probiotics (Lactobacillus plantarum or L. plantarum) affected oocysts per gram of feces (OPG), fecal scores, feed conversion ratio (FCR), immunomodulatory effect in terms of the cell-mediated and humoral immune response. Serum chemistry (ALT, AST, LDH, and creatinine) was measured in different treated chicken groups. mRNA expression levels of antioxidant enzymes (SOD 1 and CAT), peptide transporter 1 (PepT 1), and tight junction proteins (ZO and CLDN 1) were also examined in chicken groups infected with Eimeria tenella (E. tenella). Chickens supplemented with L. plantarum 1 × 108 CFU (colony-forming unit) showed an improved cell-mediated and humoral immune response, compared with the control group (p < 0.05). Probiotics also enhanced the performance of antioxidant enzymes, PepT 1, and tight junction proteins, and improved serum chemistry (AST, ALT, and LDH), compared with control-infected, non-medicated chickens. However, no significant difference (p > 0.05) was observed in CLDN 1 expression level and creatinine in all treated chicken groups. These findings demonstrated that probiotics supplementation in the feed can protect the birds against E. tenella infection.