Plasmodesmata: gatekeepers for cell-to-cell transport of developmental signals in plants.
Plasmodesmata: gatekeepers for cell-to-cell transport of developmental signals in plants.
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DOI：
10.1146/annurev.cellbio.16.1.393
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发表时间：
2000
影响因子：
11.3
通讯作者：
Patricia Zambryski;Katrina M. Crawford
中科院分区：
文献类型：
--
作者：
Patricia Zambryski;Katrina M. Crawford
细胞壁将单个植物细胞隔开。为了实现必要的细胞间通讯，植物进化出了膜内衬通道，称为胞间连丝，连接相邻细胞之间的细胞质。历史上，胞间连丝被认为是促进低分子量生长调节剂和对生长至关重要的营养物质的运输。大分子通过胞间连丝运输的证据仅仅是基于植物病毒在感染传播过程中对胞间连丝的利用。现在，胞间连丝被揭示运输内源性蛋白质，包括对发育重要的转录因子。两种一般类型的蛋白质，非靶向和胞间连丝靶向，交通胞间连丝通道。大小和亚细胞位置影响非靶向蛋白质转运能力。叠加在货物的具体参数，胞间连丝本身波动之间的孔关闭，开放和扩张。此外，胞间连丝改变其运输能力的发展过程中的时间和空间在不同地区的植物。胞间连丝作为信号分子的主要守门人，促进或调节发育程序，维持生理状态，并对病原体作出反应。
Cell walls separate individual plant cells. To enable essential intercellular communication, plants have evolved membrane-lined channels, termed plasmodesmata, that interconnect the cytoplasm between neighboring cells. Historically, plasmodesmata were viewed as facilitating traffic of low-molecular weight growth regulators and nutrients critical to growth. Evidence for macromolecular transport via plasmodesmata was solely based on the exploitation of plasmodesmata by plant viruses during infectious spread. Now plasmodesmata are revealed to transport endogenous proteins, including transcription factors important for development. Two general types of proteins, non-targeted and plasmodesmata-targeted, traffic plasmodesmata channels. Size and subcellular location influence non-targeted protein transportability. Superimposed on cargo-specific parameters, plasmodesmata themselves fluctuate in aperture between closed, open, and dilated. Furthermore, plasmodesmata alter their transport capacity temporally during development and spatially in different regions of the plant. Plasmodesmata are exposed as major gatekeepers of signaling molecules that facilitate or regulate developmental programs, maintain physiological status, and respond to pathogens.