Meta-analysis of meta-analyses of anterior cruciate ligament injury reduction training programs
Meta-analysis of meta-analyses of anterior cruciate ligament injury reduction training programs
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DOI：
10.1002/jor.24043
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发表时间：
2018-10-01
影响因子：
2.8
通讯作者：
Hewett, Timothy E.
中科院分区：
文献类型：
--
作者：
Webster, Kate E.;Hewett, Timothy E.
关于前交叉韧带（ACL）损伤预防训练计划降低ACL损伤风险的有效性，已经发表了几项荟萃分析，并报道了不同程度的风险降低。本研究的目的是对评估ACL损伤预防训练方案有效性的重叠荟萃分析进行系统回顾和荟萃分析，从而将所有ACL和非接触性ACL损伤的风险降低量总结为单一来源，并确定ACL损伤预防训练方案的相对效果是否存在性别差异。我们检索了五个数据库（Medline、PubMed、Embase、CINAHL和Cochrane），以确定评估前交叉韧带损伤预防训练计划对前交叉韧带损伤风险有效性的荟萃分析。提取ACL损伤数据，并使用基于优势比（OR）的汇总荟萃分析合并每个荟萃分析的结果。8项荟萃分析符合入选标准。8项研究中有6项只包含了女运动员的数据。摘要荟萃分析显示，所有运动员的所有ACL损伤风险总体降低50% (OR = 0.5 [0.41-0.59]; I-2 = 15%)，女性非接触性ACL损伤风险降低67% （OR = 0.33 [0.27-0.41]; I-2 = 15%）。本文将之前所有的荟萃分析整合到一个单一的来源中，并显示出确凿的证据，即ACL损伤预防计划将所有运动员的所有ACL损伤风险降低了一半，将女性运动员的非接触性ACL损伤风险降低了三分之二。对于男性运动员ACL损伤预防方案的有效性，目前还没有足够的数据来得出结论。(c) 2018年骨科研究会。Wiley期刊公司出版。[J]中华骨科杂志，2018。
Appendix Several meta-analyses have been published on the effectiveness of anterior cruciate ligament (ACL) injury prevention training programs to reduce ACL injury risk, with various degrees of risk reduction reported. The purpose of this research was to perform a systematic review and meta-analysis of overlapping meta-analyses evaluating the effectiveness of ACL injury prevention training programs so as to summarize the amount of reduction in risk for all ACL and non-contact ACL injuries into a single source, and determine if there were sex differences in the relative efficacy of ACL injury prevention training programs. Five databases (Medline, PubMed, Embase, CINAHL, and Cochrane) were searched to identify meta-analyses that evaluated the effectiveness of ACL injury prevention training programs on ACL injury risk. ACL injury data were extracted and the results from each meta-analysis were combined using a summary meta-analysis based on odds ratios (OR). Eight meta-analyses met eligibility criteria. Six of the eight only included data for female athletes. Summary meta-analysis showed an overall 50% reduction (OR = 0.5 [0.41-0.59]; I-2 = 15%) in the risk of all ACL injuries in all athletes and a 67% reduction (OR = 0.33 [0.27-0.41]; I-2 = 15%) for non-contact ACL injuries in females. This paper combines all previous meta-analyses into a single source and shows conclusive evidence that ACL injury prevention programs reduce the risk of all ACL injuries by half in all athletes and non-contact ACL injuries by two-thirds in female athletes. There is insufficient data to make conclusions as to the effectiveness of ACL injury prevention programs in male athletes. (c) 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:2696-2708, 2018.