Executive function deficits in short-term abstinent cannabis users
Executive function deficits in short-term abstinent cannabis users
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DOI：
10.1002/hup.941
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发表时间：
2008-07-01
影响因子：
1.7
通讯作者：
Hunt, Nigel
中科院分区：
文献类型：
--
作者：
McHale, Sue;Hunt, Nigel
目的：很少有认知任务具有足够的敏感性来显示戒除慢性大麻吸毒者的表现有轻微的下降。在这一系列的三个实验中，我们开始展示各种足够敏感的任务，以显示控制组和大麻使用者在视觉记忆、言语记忆、日常记忆和执行功能方面的差异。方法一系列三项研究探讨了短期戒除大麻使用者的认知功能缺陷(音素语言流畅性、视觉识别、即时和延迟回忆以及前瞻性记忆)。采用滚雪球抽样的方法选择受试者，将吸食大麻者与标准对照组和吸烟组进行比较。结果吸食大麻者与两个对照组相比，在语言流畅性、视觉识别、延迟视觉回忆、短间隔和长间隔前瞻记忆方面都存在缺陷。在即刻视觉回忆上没有差异。结论这些发现表明吸食大麻会导致执行功能受损。进一步的研究需要探索大麻使用的长期影响。版权所有(C)2008 John Wiley&Sons，Ltd.
Objectives Few cognitive tasks are adequately sensitive to show the small decrements in performance in abstinent chronic cannabis users. In this series of three experiments we set out to demonstrate a variety of tasks that are sufficiently sensitive to show differences in visual memory, verbal memory, everyday memory and executive function between controls and cannabis users.Methods A series of three studies explored cognitive function deficits in cannabis users (phonemic verbal fluency, visual recognition and immediate and delayed recall, and prospective memory) in short-term abstinent cannabis users. Participants were selected using snowball sampling, with cannabis users being compared to a standard control group and a tobacco-use control group.Results The cannabis users, compared to both control groups, had deficits on verbal fluency, visual recognition, delayed visual recall, and short- and long-interval prospective memory. There were no differences for immediate visual recall.Conclusions These findings suggest that cannabis use leads to impaired executive function. Further research needs to explore the longer term impact of cannabis use. Copyright (c) 2008 John Wiley & Sons, Ltd.