Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning
Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning
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DOI：
10.1007/s10802-007-9165-9
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发表时间：
2008-01-01
影响因子：
3.6
通讯作者：
Vitiello, Benedetto
中科院分区：
文献类型：
--
作者：
Sukhodolsky, Denis G.;Scahill, Lawrence;Vitiello, Benedetto
背景除了核心症状外，广泛性发育障碍（PDD）儿童还经常表现出其他问题行为，如攻击、多动和焦虑，这些行为可导致整体损害，因此成为临床关注的焦点。关于这些儿童焦虑症患病率的数据有限。我们研究的频率和相关性的父母评定的焦虑症状在一个大样本的儿童PDD.Methods本研究的目标是检查的频率和相关性的父母评定的焦虑症状在一个样本中的171个药物免费的儿童PDD谁参加了两个NIH资助的药物试验。采用儿童青少年症状量表（CASI）的20个项目测量焦虑。结果43%的总样本符合至少一种焦虑障碍的筛选截止标准。在20项CASI量表上，焦虑水平越高，智商越高，功能性语言使用的存在，以及刻板行为的水平越高。在智商较高的儿童，焦虑也与更大的损害在社会reciprocity.Conclusion焦虑是常见的PDD和值得考虑的临床评估和治疗计划。这项研究表明，父母的评级可能是一个有用的信息来源，在这个人群中的焦虑症状。一些焦虑症状，如恐怖和社交焦虑可能更接近PDD的核心症状。需要进一步的努力来验证工具，以确定焦虑，因为是研究，以实证检验的方法来治疗焦虑的PDD。
Background In addition to the core symptoms, children with Pervasive Developmental Disorders (PDD) often exhibit other problem behaviors such as aggression, hyperactivity, and anxiety, which can contribute to overall impairment and, therefore, become the focus of clinical attention. Limited data are available on the prevalence of anxiety in these children. We examined frequency and correlates of parent-rated anxiety symptoms in a large sample of children with PDD.Methods The goals of this study were to examine the frequency and correlates of parent-rated anxiety symptoms in a sample of 171 medication-free children with PDD who participated in two NIH-funded medication trials. Twenty items of the Child and Adolescent Symptom Inventory (CASI) were used to measure anxiety.Results Forty three percent of the total sample met screening cut-off criteria for at least one anxiety disorder. Higher levels of anxiety on the 20-item CASI scale were associated with higher IQ, the presence of functional language use, and with higher levels of stereotyped behaviors. In children with higher IQ, anxiety was also associated with greater impairment in social reciprocity.Conclusion Anxiety is common in PDD and warrants consideration in clinical evaluation and treatment planning. This study suggests that parent ratings could be a useful source of information about anxiety symptoms in this population. Some anxiety symptoms such as phobic and social anxiety may be closer to core symptoms of PDD. Further efforts to validate tools to ascertain anxiety are needed, as are studies to empirically test approaches to treat anxiety in PDD.