ARUGOMYCIN, A NEW ANTHRACYCLINE ANTIBIOTIC .2. STRUCTURAL ELUCIDATION
ARUGOMYCIN, A NEW ANTHRACYCLINE ANTIBIOTIC .2. STRUCTURAL ELUCIDATION
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DOI：
10.7164/antibiotics.40.1273
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发表时间：
1987-09-01
影响因子：
3.3
通讯作者：
OTAKE, N
中科院分区：
文献类型：
--
作者：
KAWAI, H;HAYAKAWA, Y;OTAKE, N
通过化学降解、核磁共振和质谱分析，确定了它的结构，它是一种新的蒽环类抗生素，以arugorol（4“-epi-nogalarol）为发色团，含有2个糖链，即diginosyl-decilonitrosyl-2-deoxyfucosyl-diginose和（4-O-fumaryl-diginosyl）-diginosyl-2-deoxyfucosyl-diginose。
The structure of arugomycin was determined by chemical degradation, and NMR and mass spectral analyses to be a new anthracycline antibiotic with arugorol (4''-epi-nogalarol) as the chromophore and two sugar chains comprising diginosyl-decilonitrosyl-2-deoxyfucose, and (4-O-fumaryl-diginosyl)-diginosyl-2-deoxyfucosyl-diginose.