Zinc deficiency in Mexican American children: influence of zinc and other micronutrients on T cells, cytokines, and antiinflammatory plasma proteins

Zinc deficiency in Mexican American children: influence of zinc and other micronutrients on T cells, cytokines, and antiinflammatory plasma proteins
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DOI:
10.1093/ajcn/88.4.1067
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发表时间:
2008-10-01
影响因子:
7.1
通讯作者:
Zavaleta, Antonio N.
Zavaleta, Antonio N.
中科院分区:
医学1区
文献类型:
--
作者:
Sandstead, Harold H.;Prasad, Ananda S.;Zavaleta, Antonio N.

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背景资料:第三次全国健康和营养检查调查表明,一些墨西哥裔美国儿童有缺锌的风险。目的:我们测量了锌和微量营养素或单独微量营养素对细胞介导的免疫和血浆蛋白指数的影响。设计:受试者(n = 54),年龄6-7岁,随机分配和治疗,在双盲的方式,在同等数量的锌20毫克结果:治疗前平均+/- SD血浆锌为14.9 +/- 1.7 μ mol/ dL,范围在参考范围内;发锌为1.78 ± 0.52 μ mol/g,
Background: The Third National Health and Nutrition Examination Survey suggested some Mexican American children are at risk of zinc deficiency.Objective: We measured the effects of zinc and micronutrients or of micronutrients alone on indexes of cell-mediated immunity and antiinflammatory plasma proteins.Design: Subjects ( n = 54) aged 6-7 y were randomly assigned and treated in double-blind fashion in equal numbers with 20 mg Zn (as sulfate) and micronutrients or with micronutrients alone 5 d/wk for 10 wk.Results: Before treatment the mean +/- SD plasma zinc was 14.9 +/- 1.7 mu mol/ dL and the range was within the reference; hair zinc was 1.78 +/- 0.52 mu mol/g and 41.6% were