Continuing regular exercise during pregnancy: Effect of exercise volume on fetoplacental growth

Continuing regular exercise during pregnancy: Effect of exercise volume on fetoplacental growth
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DOI:
10.1067/mob.2002.119109
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发表时间:
2002-01-01
影响因子:
9.8
通讯作者:
Lopez, B
Lopez, B
中科院分区:
医学1区
文献类型:
--
作者:
Clapp, JF;Kim, H;Lopez, B

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目的:本研究的目的是检验怀孕期间不同时间的运动量对胎儿胎盘生长没有影响的零假设。研究设计:75 名定期运动的女性在怀孕前接受评估,并在妊娠 8 周时随机分配至 3 种运动方案中的一种,以用于剩余的妊娠期。主要结局变量包括胎盘生长率、出生体重和足月胎盘体积。 结果:与第 20 周后随机分配减少运动量的妇女所生的后代相比,在妊娠中后期随机分配进行高运动量的妇女所生的后代明显更轻(3.39 公斤 vs 3.81 公斤)和更瘦(8.3% 脂肪 vs 12.1% 脂肪)。高低组的孕妇体重增加、新鲜胎盘体积和胎盘功能的组织形态学指数更大。结论:这些数据表明,妊娠中后期进行大量中等强度的负重运动会对称地降低胎儿胎盘的生长,而运动量的减少会促进胎儿胎盘的生长,脂肪量的增加比例大于去脂体重的增加。
OBJECTIVE: The purpose of this study was to test the null hypothesis that the volume of exercise at different times during pregnancy has no effect on fetoplacental growth.STUDY DESIGN: Seventy-five women who exercised regularly were evaluated before pregnancy and randomly assigned at 8 weeks' gestation to one of 3 exercise regimens for the remainder of pregnancy. Primary outcome variables included placental growth rate, birth weight, and placental volume at term.RESULTS: The offspring of the women who were randomly assigned to a high volume of exercise In mid and late pregnancy were significantly lighter (3.39 kg vs 3.81 kg) and thinner (8.3% fat vs 12.1% fat) than those offspring born of women who were randomly assigned to reduce their exercise volume after the 20th week. Maternal weight gain, fresh placental volumes, and histomorphometric indices of placental function were greater in the high-low group.CONCLUSION: These data indicate that a high volume of mode rate-intensity, weight-bearing exercise In mid and late pregnancy symmetrically reduces fetoplacental growth, whereas a reduction in exercise volume enhances fetoplacental growth with a proportionally greater increase in fat mass than in lean body mass.