Apolipoprotein A-I-containing lipoproteins, with or without apolipoprotein A-II, as progenitors of pre-beta high-density lipoprotein particles.

Apolipoprotein A-I-containing lipoproteins, with or without apolipoprotein A-II, as progenitors of pre-beta high-density lipoprotein particles.
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含有载脂蛋白 A-I 的脂蛋白,有或没有载脂蛋白 A-II,作为前 β 高密度脂蛋白颗粒的祖细胞。

DOI:
10.1021/bi00073a006
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发表时间:
1993
期刊:
影响因子:
2.9
通讯作者:
Kane,JP
Kane,JP
中科院分区:
生物学3区
文献类型:
--
作者:
Hennessy,LK;Kunitake,ST;Kane,JP

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所有)和Lp(AI+所有)的流动性,而这两个异质亚部分,有许多共同的总特征。这两个亚组分主要是球形的形状,具有相似的构象apoA-I的圆二色性和特定的内切蛋白酶的研究,并具有相似的含量的磷脂,磷脂类,甘油三酯,和胆固醇酯。然而,在Lp(AI-10%)中有显著更少的蛋白质(-10%)和更多的游离胆固醇(+46%)。
All) and Lp (AI+ All) of a mobility, while both heterogeneous subfractions, share many gross features in common. Both subfractions were predominantly spherical in shape, had similar conformation of apoA-I as investigated by circular dichroism and specific endoproteases, and had similar contents of phospholipids, phospholipid species, triglycerides, and cholesterol ester. However, there was significantly less protein (-10%) and more free cholesterol (+ 46%) in the Lp (AI-