Polyketides and Meroterpenoids from Neosartorya glabra
Polyketides and Meroterpenoids from Neosartorya glabra
复制标题
光新萨托利亚的聚酮化合物和小萜类化合物
DOI:
10.1002/hlca.201400231
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发表时间:
2015-04-01
影响因子:
1.8
通讯作者:
Yu, Qin
中科院分区:
文献类型:
--
作者:
Liu, Wen-Hong;Zhao, Hong;Yu, Qin
Two new polyketides, neosarphenols A and B (1 and 2, resp.), were isolated from Neosartorya glabra, together with six known polyketides, 3 - 8, and two meroterpenoids, 9 and 10. The structures of the new compounds were elucidated by comprehensive spectroscopic analysis, especially by HR-ESI-MS and NMR experiments. All compounds were evaluated for their cytotoxic activities against MDA-MB-231, MCF-7, and PANC-1 tumor cell lines; 1 and 6 exhibited selective and moderate cytotoxicities against PANC-1 cell line.