TRANSMISSION OF ARBOVIRUSES TO HAMSTERS BY BITE OF NATURALLY INFECTED CULEX (MELANOCONION) MOSQUITOES
TRANSMISSION OF ARBOVIRUSES TO HAMSTERS BY BITE OF NATURALLY INFECTED CULEX (MELANOCONION) MOSQUITOES
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DOI：
10.4269/ajtmh.1967.16.525
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发表时间：
1967-01-01
影响因子：
3.3
通讯作者：
SRIHONGSE, S
中科院分区：
文献类型：
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作者：
GALINDO, P;SRIHONGSE, S
在巴拿马Almirante捕获的11，598只野生雌性库蚊和229只其他库蚊（黑锥）标本被允许以54只实验室饲养的仓鼠为食。氏梭vomerifer与仓鼠接触，观察到3987只仓鼠充血。在被C.一株Ossa病毒是从被库蚊取食的仓鼠身上获得的。带足虫C.从被这些蚊子叮咬的仓鼠的组织中分离出病原体，鉴定出vomerifer，5株Ossa病毒和4株马德里病毒。通过对存活仓鼠的血清进行针对27种不同虫媒病毒抗原的HI [血凝抑制]和CF [补体结合]试验，证实并鉴定了其他9种传播，即5种瓜马病毒，以及奥萨、马德里、帕图瓦和马亚罗病毒各1种。所有传播的5种病毒以前都已知发生在阿尔米兰特地区，其中4种在那里经常遇到。C. vomerifer是Almirante的Ossa、马德里和Guama病毒的经证实的载体，其中前两种病毒是人类的重要病原体。在研究区域，它不是VEE [委内瑞拉马脑炎]的有效载体，尽管经常发现它携带这种病毒剂。种C.当达到高种群高峰时，带虫可能是骨病毒和其他虫媒病毒的载体。
A total of 11,598 wild-caught female of Culex vomerifer and 229 specimens of other species of Culex (Melanoconion) mosquitoes captured in Almirante, Panama, were allowed to feed on 54 laboratory-bred hamsters. Of the C. vomerifer given access to hamsters, 3987 were observed to engorge on blood. A total of 18 transmissions of arboviruses were demonstrated in hamsters bitten by C. vomerifer mosquitoes, and one strain of Ossa virus was obtained from a hamster fed on by C. taeniopus. Nine of the transmissions by C. vomerifer, 5 of Ossa virus, and 4 of Madrid virus, were identified by isolation of the agents from the tissues of hamsters bitten by these mosquitoes. The other 9 transmissions, five of Guama, and one each of Ossa, Madrid, Patois, and Mayaro viruses, were demonstrated and identified by subjecting the serum of surviving hamsters to HI [hemagglutination inhibition] and CF [complement fixation] tests against antigens of 27 different arboviruses. All 5 viruses transmitted were previously known to occur in the Almirante area, and 4 of them are commonly encountered there. C. vomerifer is a proved vector of Ossa, Madrid, and Guama viruses in Almirante, the first 2 of which are important pathogens to human beings. It is not an efficient vector of VEE [Venezulian equine encephalitis] in the study area even though it is frequently found harboring this viral agent. The species C. taeniopus may be a vector of Ossa and perhaps of other arboviruses when high population peaks are attained.