Clinical Monitoring of Early Caries Lesions using Cross Polarization Optical Coherence Tomography.
Clinical Monitoring of Early Caries Lesions using Cross Polarization Optical Coherence Tomography.
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DOI：
10.1117/12.2011014
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发表时间：
2013-03-25
期刊：
影响因子：
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通讯作者：
Pelzner, Roger B
中科院分区：
文献类型：
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作者：
Fried, Daniel;Staninec, Michal;Pelzner, Roger B
需要新的方法来无损测量牙齿脱矿和再矿化，并监测早期龋齿病变（蛀牙）的进展，以进行有效的非手术干预，并评估抗龋齿治疗，如化学治疗或激光照射的性能。研究表明，光学相干断层扫描（OCT）有很大的潜力，以履行这一角色，因为它可以用来测量的深度和严重性的早期病变的轴向分辨率超过10微米。该方法易于在体应用，可用于牙齿咬合面的复杂形貌成像。在本文中，我们介绍了两项正在进行的临床研究的早期结果，以衡量氟干预对早期病变的影响。使用CP-OCT监测氟保护漆干预前后牙釉质和牙根表面的早期病变。所有检查的病变的病变深度和内部结构都得到了解决，一些病变具有明确的低反射率表面区域，这可能表明病变被阻止。氟干预后，一些病变的结构也发生了变化。
New methods are needed for the nondestructive measurement of tooth demineralization and remineralization and to monitor the progression of incipient caries lesions (tooth decay) for effective nonsurgical intervention and to evaluate the performance of anti-caries treatments such as chemical treatments or laser irradiation. Studies have shown that optical coherence tomography (OCT) has great potential to fulfill this role, since it can be used to measure the depth and severity of early lesions with an axial resolution exceeding 10-mum. It is easy to apply in vivo and it can be used to image the convoluted topography of tooth occlusal surfaces. In this paper we present early results from two clinical studies underway to measure the effect of fluoride intervention on early lesions. CP-OCT was used to monitor early lesions on enamel and root surfaces before and after intervention with fluoride varnish. The lesion depth and internal structure were resolved for all the lesions examined and some lesions had well defined surface zones of lower reflectivity that may be indicative of arrested lesions. Changes were also noted in the structure of some of the lesions after fluoride intervention.