Item-by-item factor analysis of the Yale-Brown obsessive compulsive scale symptom checklist
Item-by-item factor analysis of the Yale-Brown obsessive compulsive scale symptom checklist
复制标题
DOI：
10.1176/appi.neuropsych.15.2.187
复制
发表时间：
2003-03-01
影响因子：
2.9
通讯作者：
Liebowitz, MR
中科院分区：
文献类型：
--
作者：
Feinstein, SB;Fallon, BA;Liebowitz, MR
强迫症的临床亚型可能具有不同的病理生理机制和治疗结果。由耶鲁 - 布朗强迫症量表（Y - BOCS）症状检查表确定的、通过临床共识聚类的亚型从未经过统计验证。对160名强迫症患者样本进行了因素分析，以确定通过因素分析得出的类别是否与现有的临床确定类别相同。我们的分析显示，Y - BOCS症状检查表的污染亚型包含两个不同的亚组：一个与不适感有关，另一个与对伤害的恐惧有关。如果在更大规模上得到重复验证，新的亚型分组的发现将对强迫症的未来研究具有重要意义。
Clinical subtypes of obsessive-compulsive disorder may have differing pathophysiological mechanisms and treatment outcomes. The subtypes identified by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) Symptom Checklist, clustered by clinical consensus, have never been subject to statistical validation. A factor analysis using a sample of 160 patients with OCD was conducted to determine whether factor analytically derived categories are identical to extant clinically determined categories. Our analysis revealed that the contamination subtype of the Y-BOCS Symptom Checklist contains two distinct subgroups: one relating to discomfort and the other to fear of harm. If replicated on a larger scale, the finding of new subtype groupings would have important implications for future research in obsessive-compulsive disorder.