Neuronal control of microvessels.

Neuronal control of microvessels.
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微血管的神经元控制。

DOI:
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发表时间:
1980
影响因子:
18.2
通讯作者:
S. Rosell
S. Rosell
中科院分区:
医学1区
文献类型:
--
作者:
S. Rosell

文献摘要

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大多数关于神经元控制微循环的研究都涉及整个器官的血流量、组织体积或毛细血管过滤的测量(61)。因此,对维管床的不同串联耦合截面的响应进行了计算。毛细管前和毛细管后电阻截面、交换截面和毛细管后电容截面通常是基于这些测量。只有少数研究涉及到神经活动中单个血管的体内直接观察。因此,本综述主要基于全器官测量的数据。关于心血管控制机制源自高级脑结构(81)和稳态反射机制的全面描述已经发表(66)。这一综述仅限于局部神经控制机制,近年来也对这一主题进行了综述(61,77)。一篇优秀的综述(61)详细讨论了骨骼肌、皮肤和肠道血管床的控制系统,包括神经控制。本文总结了最近提出的一些假设和有关的新数据:(a)血管阻力和电容的神经控制;(b)血管通透性的神经控制;(c)微循环的pep - tideric神经控制。
Most studies of the neuronal control of the microcirculation have involved whole organ measurements of blood flow, tissue volume, or capillary filtra­ tion (61). Consequently, accounts of the responses of the different series­ coupled sections of a vascular bed-i.e. the preand postcapillary resistance sections, exchange section and postcapillary capacitance section-are usu­ ally based on such measurements. Only a few studies have involved direct observations in vivo of single vessels during nerve activity. The present review is thus based mainly on data from whole organ measurements. Comprehensive descriptions of the cardiovascular control mechanisms emanating from higher brain structures (81) and of homeostatic reflex mechanisms have been published (66). This review is limited to the local nervous control mechanisms, a topic also reviewed in recent years (61, 77). An excellent review (61) discusses in detail the control systems, including nervous control, of the vascular beds of skeletal muscle, skin, and intestine. The present survey summarizes some of the recently developed hypotheses and new data related to (a) nervous control of vascular resistance and capacitance; (b) nervous control of vascular permeability; and (c) the pep­ tidergic nervous control of the microcirculation.