Performance characteristics of gas analysis systems: What we know and what we need to know
Performance characteristics of gas analysis systems: What we know and what we need to know
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DOI：
10.1055/s-2004-830505
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发表时间：
2005-02-01
影响因子：
2.5
通讯作者：
Nevill, AM
中科院分区：
文献类型：
--
作者：
Atkinson, G;Davison, RCR;Nevill, AM
重要的是，在气体分析测量变化的来源是确定和描述准确和信息的方式。在本文中，我们讨论了在气体分析系统的任何测量研究中应该考虑的潜在误差来源。然后，我们介绍了与气体定律相关的各种术语的误差如何传播到气体交换的结果测量中，以帮助量化误差源的相对重要性。最后，我们进行了文献调查，探讨了研究人员所采用的统计方法，得出了气体分析方法性能特征的结论。我们在文献中找到了优秀实践的例子，但在气体分析系统的误差知识方面也存在空白。因此，我们为未来的方法比较研究提供了指导方针。这些指南包括(i)至少40名参与者的样本量和置信区间的引用，（ii）描述系统误差和随机误差与测量值大小之间的关系，（iii）方法比较研究中测试-重测误差的平行检查，以及（iv）优先判断方法之间的系统误差和随机误差在实际应用中是可接受的。我们强调，这种判断应该基于专家同意的关于可接受误差的立场声明，不幸的是，这还没有为气体分析系统制定。
It is important that sources of variation in gas analysis measurements are identified and described in an accurate and informative manner. In this paper, we discussed the potential sources of error, which should be considered in any measurement study on gas analysis systems. We then covered how errors in various terms associated with gas laws propagate to outcome measurements of gas exchange to help quantify the relative importance of sources of error. Finally, we performed a literature survey to explore the statistical methods researchers have employed to arrive at conclusions on the performance characteristics of gas analysis methods. We found examples of excellent practice in the literature, but there were also gaps in the knowledge of error in gas analysis systems. Consequently, we supplied guidelines for future method comparison studies. These guidelines included (i) a sample size of at least 40 participants and the citation of confidence intervals, (ii) a description of the relationships between systematic and random errors and the size of measured value, (iii) the parallel examination of test-retest error within a method comparison study, and (iv) an a priori-made judgement on how much systematic and random error between methods is acceptable for practical applications. We stressed that this judgement should be based on expert-agreed position statements about acceptable error, which unfortunately have yet to be formulated for gas analysis systems.