ELECTROENCEPHALOGRAPHIC EXAMINATION OF EPILEPTIC DOGS UNDER PROPOFOL RESTRAINT
ELECTROENCEPHALOGRAPHIC EXAMINATION OF EPILEPTIC DOGS UNDER PROPOFOL RESTRAINT
复制标题
DOI：
10.1556/avet.2012.026
复制
发表时间：
2012-09-01
影响因子：
0.9
通讯作者：
Halasz, Peter
中科院分区：
文献类型：
--
作者：
Pakozdy, Akos;Thalhammer, Johann G.;Halasz, Peter
本研究的主要目的是确定一组已知病因癫痫发作（症状性癫痫，SE）和特发性癫痫（IE）犬的发作间期癫痫样放电。所有犬均使用丙泊酚进行化学束缚。我们发现脑电图（EEG）的变化，可以被认为是癫痫样放电（ED）在5 40只狗（12.5%）。脑电图的变化确定的尖峰在4例和周期性癫痫样放电的情况下。所有ED均见于SE组。我们的结论是，发作间期脑电图检查的丙泊酚麻醉的狗患有IE和SE很少显示癫痫放电，这种脑电图在癫痫的诊断价值似乎是低的癫痫放电不太可能被检测到。然而，阳性结果更可能与SE有关。我们发现了频繁的瞬态EEG现象（纺锤波、K复合波、顶点波、睡眠的正枕尖瞬态、周期性交替模式），这些现象是非癫痫性的，但将其与癫痫现象区分开来具有挑战性。
The main aim of this study was to identify interictal epileptiform discharges in a group of dogs with seizures of known aetiology (symptomatic epilepsy, SE) and in dogs with idiopathic epilepsy (IE). Propofol was used for chemical restraint in all dogs. We found electroencephalographic (EEG) changes that could be considered epileptiform discharges (EDs) in 5 out of 40 dogs (12.5%). The EEG changes identified were spikes in four cases and periodic epileptiform discharges in one case. All EDs were seen in the SE group. We conclude that the interictal electroencephalographic examinations of propofolanaesthetised dogs suffering from IE and SE rarely show epileptic discharges and that the diagnostic value of such EEGs in the work-up for epilepsy seems to be low as epileptic discharges were unlikely to be detected. However, positive findings are more likely to be connected with SE. We found frequent, transient EEG phenomena (spindles, K-complexes, vertex waves, positive occipital sharp transients of sleep, cyclic alternating patterns), which are non-epileptic but their differentiation from epileptic phenomena is challenging.