Diastereoselective Hydroxyethylation of ß -Hydroxyketones: A Reformatsky Cyclization-Lactone Reduction Cascade Mediated by SmI 2 -H 2 O
Diastereoselective Hydroxyethylation of ß -Hydroxyketones: A Reformatsky Cyclization-Lactone Reduction Cascade Mediated by SmI 2 -H 2 O
复制标题
α-羟基酮的非对映选择性羟乙基化：由 SmI 2 -H 2 O 介导的 Reformatsky 环化-内酯还原级联
DOI：
10.1002/hlca.201900227
复制
发表时间：
2019
影响因子：
1.8
通讯作者：
Garduño-Castro M
中科院分区：
文献类型：
--
作者：
Garduño-Castro M
β -羟基酮的羟乙基化允许非对映选择性地获得重要的1,3,5 -三醇。该方法利用SmI2 - H2O介导的Reformatsky环化-内酯还原级联。
The hydroxyethylation of β‐hydroxyketones allows diastereoselective access to important 1, 3, 5‐triols. The approach exploits a SmI2− H2O‐mediated Reformatsky cyclization‐lactone reduction cascade.