[Pharmacologic analysis of the radiation-protecting effect of indraline].

[Pharmacologic analysis of the radiation-protecting effect of indraline].
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吲哚林防辐射作用的药理学分析[J].

DOI:
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发表时间:
2001
期刊:
Radiatsionnaia biologiia, radioecologiia
影响因子:
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通讯作者:
V. I. Kovtun
V. I. Kovtun
中科院分区:
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文献类型:
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作者:
M. V. Vasin;I. Ushakov;L. Semenova;V. I. Kovtun

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在比较研究选择性α_1-肾上腺素受体阻滞剂哌唑核苷对吲哚青碱和美索酮的辐射防护作用时,发现它们的辐射防护作用的机制完全是通过α_1-肾上腺素能作用实现的。钙拮抗剂硝苯地平不能阻断该效应。讨论了将吲哚青碱归类为拟肾上腺素α1B的问题。
In comparative studies of the influence of selective alpha 1-adrenoblockager prazosine on radioprotective effect of indraline and mesotone it was found that the mechanism for their radioprotective effect was completely realized via alpha 1-adrenergic action. Calcium blockager nifedipine did not block the indraline effect. It was discussed the issue of classifying of indraline as alpha 1B-adrenomimetic.