(Liquid plus liquid) equilibria and extraction capacity of (imidazolium ionic liquids plus potassium tartrate) aqueous two-phase systems
(Liquid plus liquid) equilibria and extraction capacity of (imidazolium ionic liquids plus potassium tartrate) aqueous two-phase systems
复制标题
(咪唑鎓离子液体加酒石酸钾)水两相体系的(液加液)平衡和萃取能力
DOI：
10.1016/j.molliq.2013.12.022
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发表时间：
2014-05-01
影响因子：
6
通讯作者：
Ni, Liang
中科院分区：
文献类型：
--
作者：
Han, Juan;Wang, Yun;Ni, Liang
为了探索双水相体系的大范围应用，离子液体(IL)和有机盐最近被报道能够形成双水相体系。因此，在分离和提纯生物分子的生物技术应用中，它们可能是有趣的媒介。本文测定了298.15 K下1-丁基-3-甲基咪唑氯([C(4)MIM]Cl)/1-己基-3-甲基咪唑氯([C(6)MIM]Cl)/1-苄基-3-甲基咪唑氯([C(7)H(7)MIRN]Cl)-K(2)C(4)H(4)O(6)ILATPS的相图和相线。结果表明，阳离子烷基链长越大，IL形成ATPS的能力越强，同时随着阳离子烷基链长的增加，连接线斜率增大。此外，通过将所研究的ILATPS应用于氯霉素的提取，对其萃取能力进行了评价。得到的CAP在IL-K2C4H4O6 ILATPS中的分配系数顺序为：[C(6)min]Cl>；[C7H7mim]Cl>；[C(7)H(7)mim]Cl。此外，随着体系温度的升高和溶质初始浓度的增加，CAP更容易进入顶相。(C)2013爱思唯尔B.V.保留所有权利。
To explore the large range of aqueous two-phase system (ATPS) applications, ionic liquid (IL) and organic salt have been recently reported to be able to form ATPS. They could thus be interesting media in biotechnological applications for the separation and purification of biomolecules. In this work, phase diagrams and tie-lines for the 1-butyl-3-methylimidazolium chloride ([C(4)mim]Cl)/1-hexyl-3-methylimidazolium chloride ([C(6)mim]Cl)/1-benzy1-3-methylimidazolium chloride ([C(7)H(7)mirn]Cl)-K(2)C(4)H(4)O(6)ILATPSs at 298.15 K were measured and presented. It is shown that the larger the cation alkyl chain is, the greater is the IL's ability for ATPS formation, meanwhile the slope of tie-line increases with the increase of cation alkyl chain length. In addition, the extraction capacity of the studied ILATPSs was evaluated through their application to the extraction of chloramphenicol. The partition coefficient of CAP obtained in the IL-K2C4H4O6 ILATPS is followed in the order: [C(6)min]Cl > [C7H7 mim]Cl > [C(7)H(7)mim]Cl. Moreover, the CAP easily enters the top phase with the increase of temperature of the systems and initial concentration of the solute. (C) 2013 Elsevier B.V. All rights reserved.