Higher-order thalamic relays burst more than first-order relays.
Higher-order thalamic relays burst more than first-order relays.
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高阶丘脑继电器比一阶丘脑继电器爆发更多。
DOI：
10.1073/pnas.0502843102
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Sherman,SM
中科院分区：
文献类型：
--
作者：
Ramcharan,EJ;Gnadt,JW;Sherman,SM
动物的行为与丘脑中继神经元的放电模式（爆发或强直）之间存在很强的相关性。一阶和高阶丘脑中继（分别将外围信息中继到皮层和将信息从一个皮层区域中继到另一个皮层区域）之间的某些差异表明，在高阶中继中可能会发生更多的爆发。因此，我们记录了爆发行为的单细胞从清醒的，表现恒河猴在一阶（外侧膝状体核，腹后核，和内侧膝状体核的腹侧部分）和高阶（枕和内侧背核）丘脑继电器。我们发现，爆裂的程度显着更大的高阶比一阶继电器，这种增加爆裂与较低的自发活动在高阶继电器。如果爆发有效的信号引入新的信息到皮质区，建议，这种增加的爆发可能是更重要的皮质皮质传输比在传输的主要信息到皮质。
There is a strong correlation between the behavior of an animal and the firing mode (burst or tonic) of thalamic relay neurons. Certain differences between first- and higher-order thalamic relays (which relay peripheral information to the cortex versus information from one cortical area to another, respectively) suggest that more bursting might occur in the higher-order relays. Accordingly, we recorded bursting behavior in single cells from awake, behaving rhesus monkeys in first-order (the lateral geniculate nucleus, the ventral posterior nucleus, and the ventral portion of the medial geniculate nucleus) and higher-order (pulvinar and the medial dorsal nucleus) thalamic relays. We found that the extent of bursting was dramatically greater in the higher-order than in the first-order relays, and this increased bursting correlated with lower spontaneous activity in the higher-order relays. If bursting effectively signals the introduction of new information to a cortical area, as suggested, this increased bursting may be more important in corticocortical transmission than in transmission of primary information to cortex.