The mucin degrader Akkermansia muciniphila is an abundant resident of the human intestinal tract
The mucin degrader Akkermansia muciniphila is an abundant resident of the human intestinal tract
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DOI：
10.1128/aem.01226-07
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发表时间：
2008-03-01
影响因子：
4.4
通讯作者：
de Vos, Willem M.
中科院分区：
文献类型：
--
作者：
Derrien, Muriel;Collado, M. Carmen;de Vos, Willem M.
设计并验证了一种16S rrna靶向探针MUC-1437，以测定黏液蛋白降解物嗜粘蛋白Akkermansia muciniphila在人肠道中的存在和数量。通过荧光原位杂交测定，a . muciniphild占粪便细胞总数的1%以上，是人类肠道中常见的细菌成分。
A 16S rRNA-targeted probe, MUC-1437, was designed and validated in order to determine the presence and numbers of cells of Akkermansia muciniphila, a mucin degrader, in the human intestinal tract. As determined by fluorescent in situ hybridization, A. muciniphild accounted more than 1% of the total fecal cells and was shown to be a common bacterial component of the human intestinal tract.