Implementation of European standards of care for cystic fibrosis - Control and treatment of infection
Implementation of European standards of care for cystic fibrosis - Control and treatment of infection
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DOI：
10.1016/j.jcf.2009.03.001
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发表时间：
2009-05-01
影响因子：
5.2
通讯作者：
Bertram, C.
中科院分区：
文献类型：
--
作者：
Elborn, J. S.;Hodson, M.;Bertram, C.
背景：囊性纤维化（CF）护理人员存在感染控制和感染治疗的一些指南，尽管实施的程度是可变的。方法：通过向487家欧洲CF中心/单位的指定医疗保健专业人员发送调查问卷，研究CF对欧洲共识指南的依从性。进行定性数据分析。结果：共回收问卷177/547份（32%）。大多数（77%）应答者实施了感染控制政策。分离洋葱伯克霍尔德菌患者在成人（95%）中比儿童（9%）更常见，并且53%的应答者对铜绿假单胞菌进行了分离。雾化粘菌素加口服环丙沙星是铜绿假单胞菌感染最常见的治疗方法（43%）。首次感染铜绿假单胞菌通常采用吸入妥布霉素治疗；41%的受访者直到肺功能恶化才进行干预。大多数急性加重的治疗时间少于推荐的时间。结论：欧洲共识指南被广泛遵守。需要改进的领域包括：及早开始治疗病情恶化，隔离感染患者，优化抗生素治疗的持续时间。(C) 2009年Elsevier B.V.代表欧洲囊性纤维化协会出版。
Background: Several guidelines oil infection control and treatment of infection exist for cystic fibrosis (CF) caregivers, although the extent of implementation is variable.Methods: Adherence to European Consensus Guidelines for CF was Studied by sending surveys to named healthcare professionals in 487 European CF centres/units. Qualitative data analysis was performed.Results: A total of 177/547 (32%) Surveys were returned. Infection control policies were implemented by most (77%) respondents. Separation of patients with Burkholderia cepacia was more common in adults (95%) than children (9%), and was implemented by 53% of respondents for Pseudomonas aeruginosa. Nebulised colistin Plus oral ciprofloxacin was the most common (43%) therapy for P. aeruginosa infection. First infections of P aeruginosa were usually treated with inhaled tobramycin; 41% of repondents did not intervene until lung function deteriorated. Most exacerbations were treated for less than the recommended period.Conclusions: European Consensus Guidelines are widely adhered to. Areas for improvement, include: initiating therapy for exacerbations early, separating infected patients and optimising duration of antibiotic therapy. (C) 2009 Published by Elsevier B.V. on behalf of European Cystic Fibrosis Society.