An Autopsy Case of Acute Pancreatitis Caused by Cholesterol Crystal Embolization.

An Autopsy Case of Acute Pancreatitis Caused by Cholesterol Crystal Embolization.
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DOI:
10.2169/internalmedicine.5524-20
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发表时间:
2021-03-15
期刊:
Internal medicine (Tokyo, Japan)
影响因子:
--
通讯作者:
Murakami K
Murakami K
中科院分区:
其他
文献类型:
--
作者:
Sato Y;Okamoto K;Fukuda M;Oyama Y;Kondo Y;Nishida H;Daa T;Togo K;Sonoda A;Fukuda K;Matsunari O;Ogawa R;Honda K;Mizukami K;Okimoto T;Kodama M;Murakami K

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胆固醇结晶栓塞(CCE)显示预后不良,并且由于大血管中的动脉粥样硬化病变引起的胆固醇栓塞可导致缺血性器官损伤。这种栓塞主要影响肾脏和皮肤,尽管也有涉及消化器官的病例报告。我们遇到一个CCE的尸检病例,主要损害消化器官,包括胰腺。患者有非特异性腹部症状或影像学表现。对症治疗未能挽救他的生命。CCE可累及消化器官,因此必须与腹部病变相鉴别。此外,常规治疗可能无效,因此可能需要新的治疗方法。
Cholesterol crystal embolization (CCE) shows a poor prognosis and it can cause ischemic organ damage due to a cholesterol embolism from atherosclerotic lesions in large blood vessels. Such an embolism mainly affects the kidneys and skin, although cases involving digestive organs have also been reported. We encountered an autopsy case of CCE with damage mainly to the digestive organs, including the pancreas. The patient had non-specific abdominal symptoms or image findings. Symptomatic therapy failed to save him. CCE can involve the digestive organs, and so must be differentiated from abdominal pathologies. Moreover, conventional treatments may be ineffective, and new treatments might thus be necessary.
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