Left ventricle: Automated segmentation by using myocardial effusion threshold reduction and Intravoxel Computation at MR imaging
Left ventricle: Automated segmentation by using myocardial effusion threshold reduction and Intravoxel Computation at MR imaging
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DOI：
10.1148/radiol.2482072016
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发表时间：
2008-09-01
期刊：
影响因子：
19.7
通讯作者：
Wang, Yi
中科院分区：
文献类型：
--
作者：
Codella, Noel C. F.;Weinsaft, Jonathan W.;Wang, Yi
这项对现有患者数据的回顾分析得到了机构审查委员会的批准，并符合HIPAA的规定。不需要知情同意。这项研究的目的是开发和验证一种自动分割左心室(LV)腔的算法，该算法考虑了电影磁共振(MR)图像中的乳头状肌和/或小梁肌和部分体素，该算法被称为LV体素计算(LV-METIME)的LV心肌渗出阈值降低(LV-METIME)算法。该算法在生物模体中进行了验证，并将其结果与手动跟踪的结果以及商业自动分割软件(MASS[MR分析软件系统])的结果进行了比较。体外LV测量准确率为98.7%。在38名受试者中，LV测量和质量射血分数估算与手工追踪高度相关(R2=0.97和R2=0.95)。与手工追踪法计算的结果相比，LV计量法的计算结果较小，而质量计量法的计算结果较大，但所有结果都有很好的相关性(R2=0.99)。没有部分体素内插的左心室测量体积与手动追踪结果在统计学上是相同的(P>；0.05)。与其他方法相比，LV度量降低了观察者内和观察者间的变异性。在58%的病例中，肿块需要额外的人工干预，而左心室测量不需要额外的校正。LV量度可靠且可重复测量的LV体积。(C)RSNA，2008年。
This retrospective analysis of existing patient data had institutional review board approval and was performed in compliance with HIPAA. No informed consent was required. The purpose of the study was to develop and validate an algorithm for automated segmentation of the left ventricular (LV) cavity that accounts for papillary and/or trabecular muscles and partial voxels in cine magnetic resonance (MR) images, an algorithm called LV Myocardial Effusion Threshold Reduction with Intravoxel Computation (LV-METRIC). The algorithm was validated in biologic phantoms, and its results were compared with those of manual tracing, as well as those of a commercial automated segmentation software (MASS [MR Analytical Software System]), in 38 subjects. LV-METRIC accuracy in vitro was 98.7%. Among the 38 subjects studied, LV-METRIC and MASS ejection fraction estimations were highly correlated with manual tracing (R-2 = 0.97 and R-2 = 0.95, respectively). Ventricular volume estimations were smaller with LV-METRIC and larger with MASS than those calculated by using manual tracing, though all results were well correlated (R-2 = 0.99). LV-METRIC volume measurements without partial voxel interpolation were statistically equivalent to manual tracing results (P > .05). LV-METRIC had reduced intraobserver and interobserver variability compared with other methods. MASS required additional manual intervention in 58% of cases, whereas LV-METRIC required no additional corrections. LV-METRIC reliably and reproducibly measured LV volumes. (C) RSNA, 2008.