Mitotic DNA damage and replication checkpoints in yeast

Mitotic DNA damage and replication checkpoints in yeast
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DOI:
10.1016/s0955-0674(98)80118-x
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发表时间:
1998-12-01
影响因子:
7.5
通讯作者:
Russell, P
Russell, P
中科院分区:
生物学2区
文献类型:
--
作者:
Rhind, N;Russell, P

文献摘要

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对芽殖酵母和裂殖酵母中 G(2)/M 检查点遗传学的研究产生了许多检查点生物学的定义概念。检查点基因产物的生物化学的最新进展正在为我们的模型增加机制理解,并识别检查点针对的正常细胞周期机制的组成部分。
Studies of the genetics of G(2)/M checkpoints in budding and fission yeasts have produced many of the defining concepts of checkpoint biology. Recent progress in the biochemistry of the checkpoint gene products is adding a mechanistic understanding to our models and identifying the components of the normal cell cycle machinery that are targeted by checkpoints.