INFLAMMATORY DEMYELINATING POLYRADICULITIS IN A PATIENT WITH MULTIPLE-SCLEROSIS
INFLAMMATORY DEMYELINATING POLYRADICULITIS IN A PATIENT WITH MULTIPLE-SCLEROSIS
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DOI：
10.1001/archneur.1981.00510020057008
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发表时间：
1981-01-01
影响因子：
--
通讯作者：
SCHNABERTH, G
中科院分区：
文献类型：
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作者：
LASSMANN, H;BUDKA, H;SCHNABERTH, G
一例多发性硬化症（MS）发生，在中枢神经系统有近期脱髓鞘斑块，脊髓根周围（雪旺细胞）部分有炎症性脱髓鞘和再髓鞘。外周神经系统（PNS）病变表现为炎症、原发性节段性脱髓鞘、髓鞘剥离、神经内膜内出现含脂碎片的巨噬细胞和再髓鞘形成。这显然是多发性硬化症中中枢神经系统和PNS同时发生急性炎性脱髓鞘的第一种描述。
A case of multiple sclerosis (MS) occurred in which there were recent demyelinated plaques in the CNS, and inflammatory demyelination and remyelination in the peripheral (Schwann cell) portions of the spinal roots. The lesions in the peripheral nervous system (PNS) were characterized by inflammation, primary segmental demyelination, myelin stripping, the occurrence of lipid debris-containing macrophages in the endoneurium and remyelination. This is apparently the 1st description of simultaneous acute inflammatory demyelination in the CNS and PNS in MS.