Prognostic factors for local control and survival of cancer of the oral tongue. A retrospective analysis of 230 cases in western Sweden.
Prognostic factors for local control and survival of cancer of the oral tongue. A retrospective analysis of 230 cases in western Sweden.
复制标题
口腔舌癌局部控制和生存的预后因素。
作者：
J. Nyman;C. Mercke;J. Lindström
在1970年至1988年的19年间，瑞典西部诊断出289例口腔舌鳞状细胞癌。在其中的230例中，分析了治疗方案和结果，试图确定局部控制和生存的预后因素。肿瘤分期：T1 26%，T2 32%，T3 30%和T4 13%。32%的患者出现淋巴结疾病。60%的患者接受了手术，74%的患者接受了外部治疗，有或没有与间质照射相结合; 32%的患者接受了化疗。5年局部控制率为59%（T1 66%，T2 67%，T3 44%和T4 0%）。5年生存率为37%（T1为61%，T2为51%，T3为19%，T4为0%）。通过一个多变量的程序，我们证明了肿瘤相关的变量T-类，N-类和扩展到扁桃体区域有一个显着的生存相关性。延伸到扁桃体区域，延伸到口底和颈部淋巴结水平与局部区域控制显著相关。
During the 19-year period from 1970 to 1988, 289 cases of squamous cell carcinoma of the oral tongue were diagnosed in Western Sweden. In 230 of these, treatment regimens and results were analysed in an attempt to define prognostic factors for local control and survival. Tumour stages were: T1 26%, T2 32%, T3 30% and T4 13%. Nodal disease was seen in 32% of the patients. Sixty per cent of the patients had surgery, 74% external with or without combination with interstitial irradiation; and 32% received chemotherapy. The local control rate at five years was 59% (T1 66%, T2 67%, T3 44% and T4 0%). Survival at five years was 37% (T1 61%, T2 51%, T3 19% and T4 0%). By a multivariate procedure we demonstrate that the tumour related variables T-category, N-category and extension to the tonsillar region had a significant association with survival. Extension to the tonsillar region, extension to the floor of the mouth and level of neck nodes were significantly associated with local-regional control.