svMorph: Interactive Geometry-Editing Tools for Virtual Patient-Specific Vascular Anatomies

svMorph: Interactive Geometry-Editing Tools for Virtual Patient-Specific Vascular Anatomies
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DOI:
10.1115/1.4056055
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发表时间:
2023-03-01
影响因子:
1.7
通讯作者:
Marsden,Alison L. L.
Marsden,Alison L. L.
中科院分区:
工程技术4区
文献类型:
--
作者:
Pham,Jonathan;Wyetzner,Sofia;Marsden,Alison L. L.

文献摘要

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我们提出了svMorph,一个框架,用于交互式虚拟雕刻的患者特定的血管解剖模型。我们的框架包括三种工具,用于在管状血管几何形状中创建迂曲、动脉瘤和狭窄。这些形状编辑通过对输入模型的表面网格和血管中心线曲线进行几何操作来执行。扭曲工具还使用基于物理的定向粒子方法,结合线性混合蒙皮,以实现平滑、类似弹性的变形。我们的工具可以单独或组合应用,以生成适合模拟的变形模型。它们还与流行的血管建模软件兼容,如asimvascular。为了说明我们的工具,我们变形几个基于图像的,患者特定的模型,以创建一系列的形状变化,并通过三维,计算流体动力学模拟产生的血液动力学。我们还证明了通过自动生成相关的零维集总参数模型来快速估计形状变化的血液动力学效应的能力。
We propose svMorph, a framework for interactive virtual sculpting of patient-specific vascular anatomic models. Our framework includes three tools for the creation of tortuosity, aneurysms, and stenoses in tubular vascular geometries. These shape edits are performed via geometric operations on the surface mesh and vessel centerline curves of the input model. The tortuosity tool also uses the physics-based Oriented Particles method, coupled with linear blend skinning, to achieve smooth, elastic-like deformations. Our tools can be applied separately or in combination to produce simulation-suitable morphed models. They are also compatible with popular vascular modeling software, such assimvascular. To illustrate our tools, we morph several image-based, patient-specific models to create a range of shape changes and simulate the resulting hemodynamics via three-dimensional, computational fluid dynamics. We also demonstrate the ability to quickly estimate the hemodynamic effects of the shape changes via the automated generation of associated zero-dimensional lumped-parameter models.