Evolution and horizontal transfer of a DD37E DNA transposon in mosquitoes
Evolution and horizontal transfer of a DD37E DNA transposon in mosquitoes
复制标题
DOI：
10.1534/genetics.107.081109
复制
发表时间：
2007-12-01
期刊：
影响因子：
3.3
通讯作者：
Tu, Zhijian
中科院分区：
文献类型：
--
作者：
Biedler, James K.;Sha, Hongguang;Tu, Zhijian
1 TmD 37 E是一种独特的II类转座因子（TE），具有古老的起源，它可能参与了蚊子体内的多个水平转移，来自5属10种蚊子的ITmD 37 E序列具有很高的核苷酸（tu）同源性。例如，来自埃及伊蚊和冈比亚按蚊的ITmD 37 E序列显示出92%的nt同一性，它们都具有1.45 - 2亿年前的共同祖先。ITmD 37 E和宿主蚊子生殖的比较显示缺乏一致性。保守的ITmD 37 Es在蚊子中的广泛分布和完整拷贝的存在表明该元素可能最近很活跃。
1TmD37E, a unique class II transposable element (TE) with an ancient origin, appears to have been involved in multiple horizontal transfers in mosquitoes as ITmD37E sequences from 10 mosquito species of five genera share high nucleotide (tu) identities. For example, ITmD37E sequences from Aedes aegypti and Anopheles gambiae, which have all estimated common ancestor of 145-200 million years ago, display 92% nt identity. The comparison of ITmD37E and host mosquito phylogenies shows a lack of congruence. The wide distribution of conserved ITmD37Es in mosquitoes and the presence of intact copies suggest this element may have been recently active.