The biosynthesis of digalactosylceramide in the kidney of the C57-BL mouse.
The biosynthesis of digalactosylceramide in the kidney of the C57-BL mouse.
复制标题
C57-BL 小鼠肾脏中二半乳糖神经酰胺的生物合成。
DOI：
10.1016/0006-291x(70)90745-x
复制
发表时间：
1970
影响因子：
3.1
通讯作者：
G. M. Gray
中科院分区：
文献类型：
--
作者：
L. Coles;G. M. Gray
在存在UDP-14 C-半乳糖的情况下，雄性或雌性小鼠品系C57 BL肾脏的匀浆催化添加的葡糖神经酰胺合成乳糖神经酰胺、乳糖神经酰胺合成二半乳糖-葡糖神经酰胺以及半乳糖神经酰胺合成二半乳糖神经酰胺。含有羟基脂肪酸的神经酰胺比含有非羟基脂肪酸的神经酰胺更能刺激半乳糖神经酰胺的合成。报告了雄性和雌性组织之间的活性差异。
In the presence of UDP-14 C-galactose, homogenates of male or female mouse strain C57 BL kidneys catalysed the synthesis of lactosylceramide from added glucosylceramide, digalactosyl-glucosylceramide from lactosylceramide and digalactosylceramide from galactosylceramide. The synthesis of galactosylceramide was stimulated by ceramide containing hydroxy fatty acids rather than that with nonhydroxy fatty acids. Differences in activity between male and female tissue are reported.