COMMISSURAL COLUMNS IN THE SENSORY-MOTOR CORTEX OF MONKEYS
COMMISSURAL COLUMNS IN THE SENSORY-MOTOR CORTEX OF MONKEYS
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DOI：
10.1002/cne.901880110
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发表时间：
1979-01-01
影响因子：
2.5
通讯作者：
WISE, SP
中科院分区：
文献类型：
--
作者：
JONES, EG;COULTER, JD;WISE, SP
胼胝体投射细胞及其轴突的末端分支在猴中被鉴定[Macaca mulatta，M. fascicularis和Saimiri sciureus]感觉运动皮层的逆行和顺行标记技术，通常在同一动物中通过双重标记细胞和轴突。胼胝体纤维束终止于运动皮质（4区）和第1（SI）和第2（SII）躯体感觉区中0.5-1 mm宽的小柱状区。这些列对齐登记，以形成细长的条带，在中央前回和中央后回的长轴上向内侧延伸。在对应于手和脚的表示的区域中，区域4的显著部分SI和SII不与胼胝体连接。SI中胼胝体纤维的起源细胞主要局限于IIIB层，并形成与上述相对应的柱状和条状。在SI的连接区，胼胝体连接是相互的，精确的点到点。这和胼胝体纤维的终端分支（层I-IV）的层状分布表明，胼胝体纤维可能产生和终止于完全同伦的柱状组IIIB层锥体细胞。连合投射细胞及其末端分支并不局限于SI中特定的结构场或场的特定部分。SI的所有结构场向对侧SII异位投射。
Callosally projecting cells and the terminal ramifications of their axons were identified in the monkey [Macaca mulatta, M. fascicularis and Saimiri sciureus] sensory-motor cortex by retrograde and anterograde labeling techniques, often by double labeling cells and axons in the same animal. Bundles of callosal fibers terminate in small column-like zones 0.5-1 mm wide in the motor cortex (area 4) and in the 1st (SI) and 2nd (SII) somatic sensory areas. Such columns are aligned in register to form elongated strips extending mediolaterally in the long axes of the pre- and postcentral gyri. Significant portions of area 4, SI and SII, in regions corresponding to the representations of the hand and foot, are not callosally connected. The cells of origin of callosal fibers in SI are largely confined to layer IIIB and form columns and strips corresponding to the above. In connected zones of SI, the callosal connection is reciprocal and precisely point-to-point. This and the laminar distribution of the terminal ramifications of callosal fibers (to layers I-IV) suggest that callosal fibers may arise from and terminate upon exactly homotopic column-like groups of layer IIIB pyramidal cells. Commissurally projecting cells and their terminal ramifications are not limited to particular architectonic fields or particular parts of fields in SI. All architectonic fields of SI project heterotopically to the contralateral SII.