Identification of a Degradation Intermediate of the Momilactone A Rice Phytoalexin by the Rice Blast Fungus
Identification of a Degradation Intermediate of the Momilactone A Rice Phytoalexin by the Rice Blast Fungus
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DOI：
10.1271/bbb.110756
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发表时间：
2012-02-01
影响因子：
1.6
通讯作者：
Hasegawa, Morifumi
中科院分区：
文献类型：
--
作者：
Imai, Takuya;Ohashi, Yuko;Hasegawa, Morifumi
我们已经证明，主要的水稻二萜植物抗毒素，momilactone A，是解毒的Magnaporthe。我们在此报告了通过NMR、MS和化学合成鉴定作为降解中间体的3，6-二氧代-19-去甲-9 β-庚二烯-7，15-二烯（1）。化合物1具有与momilactone A相似的抗真菌活性，表明1是可能的脱毒化合物的前体。
We have already shown that major rice diterpene phytoalexin, momilactone A, was detoxified by Magnaporthe oryzae. We report here the identification by NMR, MS, and chemical synthesis of 3,6-dioxo-19-nor-9 beta-pimara-7,15-diene (1) as the degradation intermediate. Compound 1 exhibited similar antifungal activity to that of momilactone A, indicating 1 to be a precursor of possible detoxified compounds.