Preparation of a visible light-reactive low molecular-O-carboxymethyl chitosan (LM-O-CMCS) derivative and applicability as an anti-adhesion agent
Preparation of a visible light-reactive low molecular-O-carboxymethyl chitosan (LM-O-CMCS) derivative and applicability as an anti-adhesion agent
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DOI：
10.1007/s13233-011-0914-9
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发表时间：
2011-08
影响因子：
2.4
通讯作者：
S. Park;Siyoong Seo;H. Na;Kwang-Il Kim;Jea-woo Lee;Hee-Dong Woo;Jue-hee Lee;H. Seok;Jae-gwan Lee;Sang-in Chung;K. Chung;D. Han;Yoshihiro Ito;Euiyun Jang;T. Son
中科院分区：
文献类型：
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作者：
S. Park;Siyoong Seo;H. Na;Kwang-Il Kim;Jea-woo Lee;Hee-Dong Woo;Jue-hee Lee;H. Seok;Jae-gwan Lee;Sang-in Chung;K. Chung;D. Han;Yoshihiro Ito;Euiyun Jang;T. Son
通过在低分子-O-羧甲基壳聚糖（LM-O-CMCS）的胺基上引入糠基，合成了光反应性低分子-O-羧甲基壳聚糖（LM-O-CMCS）。制备的光反应性LM-O-CMCS的特征在于通过FTIR，1H NMR，和交联试验，而扫描俄歇电子显微镜（SAM）和MTT法用于确认细胞活力。通过水接触角测定和细胞粘附试验，考察了LM-O-CMCS作为防粘剂的适用性。
Photo-reactive low molecular-O-carboxymethyl chitosan (LM-O-CMCS) was synthesized by introducing a furfuryl group to the amine groups of LM-O-CMCS. The prepared photo-reactive LM-O-CMCS was characterized by FTIR,1H NMR, and a cross-linking test, whereas scanning Auger electron microscopy (SAM) and a MTT assay were used to confirm the cell viability. The water contact angle measurement and cell attachment test were carried out to determine the applicability of LM-O-CMCS as an anti-adhesion agent.