gQTL: A Web Application for QTL Analysis Using the Collaborative Cross Mouse Genetic Reference Population.
gQTL: A Web Application for QTL Analysis Using the Collaborative Cross Mouse Genetic Reference Population.
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DOI：
10.1534/g3.118.200230
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发表时间：
2018-07-31
期刊：
影响因子：
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通讯作者：
Threadgill DW
中科院分区：
文献类型：
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作者：
Konganti K;Ehrlich A;Rusyn I;Threadgill DW
多亲本重组近交群体，例如协作杂交（CC）小鼠遗传参考群体，越来越多地用于数量性状基因座（QTL）的分析。然而，针对这些复杂群体的专门分析软件通常是在 R 中构建的，只能在命令行上运行，这限制了许多用户对这些强大资源的使用。为了克服分析限制，我们开发了 gQTL，这是一种可通过网络访问的简单图形用户界面应用程序，基于 R 中的 DOQTL 平台，可使用来自 CC 小鼠的数据执行 QTL 作图。
Multi-parental recombinant inbred populations, such as the Collaborative Cross (CC) mouse genetic reference population, are increasingly being used for analysis of quantitative trait loci (QTL). However specialized analytic software for these complex populations is typically built in R that works only on command-line, which limits the utility of these powerful resources for many users. To overcome analytic limitations, we developed gQTL, a web accessible, simple graphical user interface application based on the DOQTL platform in R to perform QTL mapping using data from CC mice.