Effect of biotin deficiency on embryonic development in the domestic fowl

Effect of biotin deficiency on embryonic development in the domestic fowl
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DOI:
10.1002/ar.1090900109
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发表时间:
1944-09-01
期刊:
影响因子:
--
通讯作者:
Sebesta, EE
Sebesta, EE
中科院分区:
医学4区
文献类型:
--
作者:
Cravens, WW;McGibbon, WH;Sebesta, EE

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对饲喂不同水平生物素的母鸡产生的胚胎进行大体检查,以确定死亡时的大致年龄和任何胚胎异常。胚胎死亡率有两个明显的高峰。一个这样的峰发生在第一个临界期,另一个在3d临界期。胚胎中的软骨营养不良似乎是种母鸡饮食中生物素缺乏的症状之一。接受次优amts的胚胎也出现并指畸形。而在接受足够水平生物素的母鸡中则没有观察到。实验中出现的某些异常与实验结果的关系。在不同的实验条件下观察到的相似条件。条件进行了简要讨论。
Embryos produced by hens fed varying levels of biotin were examined grossly for approximate age at death and any embryonic abnormality. Two pronounced peaks in embryonic mortality were noted. One such peak occurred at the first critical period and the other at the 3d critical period. Chondro-dystrophy in the embryo appeared to be one symptom of a biotin deficiency in the diet of the breeding hen. Syn-dactyly also appeared among embryos receiving suboptimal amts. of biotin while none were observed among hens receiving adequate levels of biotin. The relation of certain abnormalities appearing during this expt. to similar conditions observed under different exptl. conditions is briefly discussed.