GLUCOSE-ABSORPTION DURING CONTINUOUS AMBULATORY PERITONEAL-DIALYSIS
GLUCOSE-ABSORPTION DURING CONTINUOUS AMBULATORY PERITONEAL-DIALYSIS
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DOI：
10.1038/ki.1981.53
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发表时间：
1981-01-01
影响因子：
19.6
通讯作者：
COBURN, JW
中科院分区：
文献类型：
--
作者：
GRODSTEIN, GP;BLUMENKRANTZ, MJ;COBURN, JW
接受持续性非卧床腹膜透析（CAPD）的患者暴露于通过其腹膜腔持续输注的葡萄糖。进行研究以定量透析液葡萄糖产生的能量。净葡萄糖吸收平均为182 . ±. (SD)在19项研究中，61 g/天，透析液葡萄糖浓度为1.5或4.25 g/dl。每升透析液中葡萄糖的吸收量（y）随透析液中葡萄糖浓度（x）的变化而变化（y = 11.3x- 10.9，r = 0.96）。在给定的透析方案中，每天吸收的葡萄糖量是恒定的。透析液葡萄糖的能量摄入为8.4 ±。2.8 kcal/kg体重/天，或总能量摄入的12-34%。这种额外的能量可能有助于CAPD期间报告的合成代谢作用。通过改变透析液葡萄糖浓度来改变葡萄糖吸收的能力可能被证明是改变能量摄入的有用工具。
Patients undergoing continuous ambulatory peritoneal dialysis (CAPD) are exposed to a continuous infusion of glucose via their peritoneal cavity. Studies were performed to quantitate the amount of energy derived from dialysate glucose. Net glucose absorption averaged 182 .+-. (SD) 61 g/day in 19 studies with a dialysate dextrose concentration of 1.5 or 4.25 g/dl. The amount of glucose absorbed per liter of dialysate (y) varied with the concentration of glucose in dislysate (x), (y = 11.3 x - 10.9, r = 0.96). The amount of glucose absorbed per day during a given dialysis regimen was constant. Energy intake from dialysate glucose was 8.4 .+-. 2.8 kcal/kg body wt per day, or 12-34% of total energy intake. This additional energy may contribute to the anabolic effect reported during CAPD. The ability to vary glucose absorption by altering the dialysate glucose concentration may prove a useful tool to modify energy intake.