Prevalence of open-angle glaucoma among adults in the United States.
Prevalence of open-angle glaucoma among adults in the United States.
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DOI：
10.1001/archopht.122.4.532
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发表时间：
2004-04
影响因子：
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通讯作者：
D. Friedman;R. Wolfs;Benita J. O’Colmain;B. Klein;H. Taylor;S. West;M. Leske;P. Mitchell;N. Congdon;J. Kempen
中科院分区：
文献类型：
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作者：
D. Friedman;R. Wolfs;Benita J. O’Colmain;B. Klein;H. Taylor;S. West;M. Leske;P. Mitchell;N. Congdon;J. Kempen
目的评估美国不同年龄、种族和性别的开角型青光眼（OAG）的患病率和分布。方法分别对黑人、西班牙裔和白色受试者进行OAG的患病率评估，从40岁开始，以5年为间隔。估计的发生率是基于最近在美国、澳大利亚和欧洲进行的基于人群的研究的荟萃分析。这些比率应用于2000年美国人口普查数据和2020年美国人口预测数据，以估计美国OAG人口的数量。结果：美国40岁及以上人群中OAG的总患病率估计为1.86%（95%置信区间，1.75%-1.96%），其中157万白色人和398000名黑人受影响。根据2000年美国人口普查的结果，将种族、年龄和性别特异性比率应用于美国人口后，我们估计OAG影响了222万美国公民。由于人口迅速老龄化，到2020年，OAG的数量将增加50%，达到336万。黑人受试者的年龄调整后青光眼患病率几乎是白色受试者的3倍。结论：在美国，开角型青光眼影响着超过200万人。由于美国人口的迅速老龄化，到2020年这一数字将增加到300多万。
OBJECTIVE To estimate the prevalence and distribution of open-angle glaucoma (OAG) in the United States by age, race/ethnicity, and gender. METHODS Summary prevalence estimates of OAG were prepared separately for black, Hispanic, and white subjects in 5-year age intervals starting at 40 years. The estimated rates were based on a meta-analysis of recent population-based studies in the United States, Australia, and Europe. These rates were applied to 2000 US census data and to projected US population figures for 2020 to estimate the number of the US population with OAG. RESULTS The overall prevalence of OAG in the US population 40 years and older is estimated to be 1.86% (95% confidence interval, 1.75%-1.96%), with 1.57 million white and 398 000 black persons affected. After applying race-, age-, and gender-specific rates to the US population as determined in the 2000 US census, we estimated that OAG affects 2.22 million US citizens. Owing to the rapidly aging population, the number with OAG will increase by 50% to 3.36 million in 2020. Black subjects had almost 3 times the age-adjusted prevalence of glaucoma than white subjects. CONCLUSIONS Open-angle glaucoma affects more than 2 million individuals in the United States. Owing to the rapid aging of the US population, this number will increase to more than 3 million by 2020.