Wavefront aberrations measured with Hartmann-Shack sensor in patients with keratoconus
Wavefront aberrations measured with Hartmann-Shack sensor in patients with keratoconus
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DOI：
10.1016/s0161-6420(02)01279-4
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发表时间：
2002-11-01
期刊：
影响因子：
13.7
通讯作者：
Tano, Y
中科院分区：
文献类型：
--
作者：
Maeda, N;Fujikado, T;Tano, Y
目的：比较正常眼和圆锥角膜眼的波前像差，并描述圆锥角膜眼高阶像差的特征。设计：前瞻性病例对照观察研究。参与者：35只圆锥角膜眼和38只正常对照眼。方法：用波前传感器测量屈光中的高阶像差，并通过视频角膜照相数据评估角膜引起的像差。主要结果测量：昏迷样（S3 + 5）、球形（S4 + 6）和总体（S3 + 4 + 5 + 6）屈光和角膜的高阶像差。S3 + 5的平均值+/-标准差（1.88 +/- 1.16），S4 + 6（0.70 +/- 0.55）和S3 + 4 + 5 + 6屈光度（2.03 +/- 1.23）（6 mm直径，均方根，p，m）在圆锥角膜眼显著高于正常对照眼（分别为0.26 +/- 0.10、0.19 +/- 0.10、0.34 +/- 0.11; Mann-Whitney U检验，P = 0.001）。圆锥角膜眼的彗差是类球面像差的2.32倍。结论：圆锥角膜眼高阶像差的增加是由于角膜高阶像差增加所致。圆锥角膜眼的像差以彗差为主，球像差次之。波前传感技术不仅可以用来评价视觉质量，而且可以通过分析高阶像差的特征来区分圆锥角膜眼和正常眼。(C)2002年由美国眼科学会，公司。
Objective: To compare the ocular wavefront aberrations of normal and keratoconic eyes and to describe the characteristics of the higher-order aberrations in eyes with keratoconus.Design: Prospective case control and observational study.Participants: Thirty-five keratoconic eyes and thirty-eight normal controls.Methods: Higher-order aberrations in refraction were measured with a wavefront sensor, and those aberrations resulting from the cornea were evaluated by videokeratographic data.Main Outcome Measures: Coma-like (S3 + 5), spherical-like (S4 + 6), and total (S3 + 4 + 5 + 6) higher-order aberrations in both refraction and the cornea.Results: The mean +/- standard deviation of S3 + 5 (1.88 +/- 1.16), S4 + 6 (0.70 +/- 0.55), and S3 + 4 + 5 + 6 (2.03 +/- 1.23) in refraction (6-mm diameter, root mean square, p,m) were significantly higher in the keratoconic eyes than in normal controls (0.26 +/- 0.10, 0.19 +/- 0.10, 0.34 +/- 0.11, respectively; Mann-Whitney U test, P = 0.001). Coma-like aberrations were 2.32 times larger than spherical-like aberrations in keratoconic eyes.Conclusions: The increase of ocular higher-order aberrations in keratoconic eyes results from an increase of corneal higher-order aberrations. Coma-like aberrations were dominant compared with spherical-like aberrations in keratoconic eyes. Wavefront sensing will enable us not only to evaluate the quality of vision but also to differentiate keratoconic eyes from normal eyes by analyzing the characteristics of the higher-order aberrations. (C) 2002 by the American Academy of Ophthalmology, Inc.