Circulating plasma angiotensin-converting enzyme 2 concentrations in patients with kidney disease.

Circulating plasma angiotensin-converting enzyme 2 concentrations in patients with kidney disease.
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肾病患者的循环血浆血管紧张素转换酶 2 浓度。

DOI:
10.1093/eurheartj/ehaa523
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发表时间:
2020
影响因子:
39.3
通讯作者:
Waikar,SushrutS
Waikar,SushrutS
中科院分区:
医学1区
文献类型:
--
作者:
Schmidt,InsaM;Verma,Ashish;Waikar,SushrutS

文献摘要

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Sama等人最近报道,在两组心力衰竭患者中,血管紧张素转换酶抑制剂(ACE-I)和血管紧张素受体阻滞剂(ARB)的使用与血浆血管紧张素转换酶2 (ACE2)水平升高无关。膜结合的ACE2是严重急性的受体
Sama et al. 1 have recently reported that angiotensin-converting enzyme inhibitor (ACE-I) and angiotensin receptor blocker (ARB) usage was not associated with higher levels of plasma angiotensinconverting enzyme 2 (ACE2) in two cohorts of patients with heart failure. Membrane-bound ACE2 is the receptor for severe acute