Mini-haplotypes as lineage informative SNPs and ancestry inference SNPs

Mini-haplotypes as lineage informative SNPs and ancestry inference SNPs
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DOI:
10.1038/ejhg.2012.69
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发表时间:
2012-11-01
影响因子:
5.2
通讯作者:
Kidd, Kenneth K.
Kidd, Kenneth K.
中科院分区:
生物学2区
文献类型:
--
作者:
Pakstis, Andrew J.;Fang, Rixun;Kidd, Kenneth K.

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我们建议,具有高杂合性的单倍型位点可以在人类识别,特别是在家庭内,如果重组是非常低的网站。三个或更多的SNP在小分子间隔上延伸(
We propose that haplotyped loci with high heterozygosity can be useful in human identification, especially within families, if recombination is very low among the sites. Three or more SNPs extending over small molecular intervals (