The Finnish Twin Cohort Study: An Update
The Finnish Twin Cohort Study: An Update
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DOI：
10.1017/thg.2012.142
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发表时间：
2013-02-01
影响因子：
0.9
通讯作者：
Kaprio, Jaakko
中科院分区：
文献类型：
--
作者：
Kaprio, Jaakko
在2002年和2006年，综述论文描述了芬兰双胞胎队列和对这些基于人群的纵向数据集进行的研究，并提供了广泛的随访数据。已经建立了三个队列：20世纪70年代的年长双胞胎队列，以及20世纪90年代开始的Finntwin 12和Finntwin 16研究。本次审查提供了自上次审查以来收集的最新数据的最新情况。这些数据涵盖了第四波数据收集，包括年龄较大的队列（1958年之前出生的双胞胎）和Finntwin 12（1983-1987年出生的双胞胎）。Finntwin 16（1975-1979年出生的双胞胎）的第五波数据收集也包括对其配偶/伴侣的评估。对1975年至2009年老年队列死亡率的分析表明，成年双胞胎（作为个体）的死亡率与总体死亡率没有差异。基于队列，已经进行或正在进行许多具有更详细表型和组学数据收集的子研究。我们还为许多国家和国际合作做出了贡献。
In 2002 and 2006, review papers have described the Finnish Twin Cohort and studies conducted on these population-based, longitudinal data sets with extensive follow-up data. Three cohorts have been established: the older twin cohort in the 1970s, and the Finntwin12 and Finntwin16 studies initiated in the 1990s. The present review provides on update on the latest data collections conducted since the previous review. These cover the fourth waves of data collection in the older cohort (twins born before 1958) and Finntwin12 (twins born 1983-1987). The fifth wave of data collection in Finntwin16 (twins born 1975-1979) also included assessments of their spouses/partners. An analysis of mortality in the older cohort from 1975 to 2009 indicates that the mortality of adult twins (as individuals) does not differ from the population at large. Based on the cohorts, many sub-studies with more detailed phenotyping and collection of omics data have been conducted or are in progress. We also contribute to numerous national and international collaborations.