Electron microscopic evaluation of a two-step theory of pore formation by streptolysin O
Electron microscopic evaluation of a two-step theory of pore formation by streptolysin O
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DOI：
10.1128/jb.178.23.6998-7002.1996
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发表时间：
1996-12-01
影响因子：
3.2
通讯作者：
Futaesaku, Y
中科院分区：
文献类型：
--
作者：
Sekiya, K;Danbara, H;Futaesaku, Y
应用免疫电镜和电子光谱成像技术研究了溶血素O（SLO）在红细胞膜和脂质体中的成孔作用。SLO分子与膜的结合不依赖于温度，而SLO分子的聚合则依赖于温度。我们的研究结果还表明，红细胞膜中的蛋白质不参与SLO环的形成。
The formation of pores by streptolysin O (SLO) was analyzed in erythrocyte membranes and liposomes by immunoelectron microscopy and electron spectroscopic imaging, The binding of SLO molecules to membranes was temperature independent, while the polymerization of SLO molecules was temperature dependent. Our results also suggest that proteins in erythrocyte membranes are not involved in the formation of SLO rings.