CT angiography after 20 years: a transformation in cardiovascular disease characterization continues to advance.
CT angiography after 20 years: a transformation in cardiovascular disease characterization continues to advance.
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DOI：
10.1148/radiol.14132232
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发表时间：
2014-06
期刊：
影响因子：
19.7
通讯作者：
Napel S
中科院分区：
文献类型：
--
作者：
Rubin GD;Leipsic J;Joseph Schoepf U;Fleischmann D;Napel S
20年前，螺旋CT(螺旋CT)和图形体积图像处理相结合，诞生了CT血管成像。在一系列CT和图像处理技术创新的推动下，在接下来的5-15年里，CT血管造影术取代了传统的血管造影术，成为诊断和表征大多数心血管异常的首选方法。本文回顾了CT血管成像从其发展和早期挑战到一种成熟的方式的演变，它为心血管疾病的特征和处理提供了独特的见解。选择的临床挑战包括急性主动脉综合征、外周血管疾病、主动脉支架移植和经导管主动脉瓣评估，以及冠状动脉疾病，作为CT血管成像如何改变我们的心血管疾病诊断和治疗方法的对比例子。最后，结合CT血管成像的不断改进和进步，探讨了最近引入的多光谱成像、组织灌注成像和通过迭代重建减少辐射剂量的能力。
Through a marriage of spiral computed tomography (CT) and graphical volumetric image processing, CT angiography was born 20 years ago. Fueled by a series of technical innovations in CT and image processing, over the next 5–15 years, CT angiography toppled conventional angiography, the undisputed diagnostic reference standard for vascular disease for the prior 70 years, as the preferred modality for the diagnosis and characterization of most cardiovascular abnormalities. This review recounts the evolution of CT angiography from its development and early challenges to a maturing modality that has provided unique insights into cardiovascular disease characterization and management. Selected clinical challenges, which include acute aortic syndromes, peripheral vascular disease, aortic stent-graft and transcatheter aortic valve assessment, and coronary artery disease, are presented as contrasting examples of how CT angiography is changing our approach to cardiovascular disease diagnosis and management. Finally, the recently introduced capabilities for multispectral imaging, tissue perfusion imaging, and radiation dose reduction through iterative reconstruction are explored with consideration toward the continued refinement and advancement of CT angiography.