3-D tomographic reconstruction of the average propagator from MRI data
3-D tomographic reconstruction of the average propagator from MRI data
复制标题
根据 MRI 数据重建平均传播器的 3D 断层扫描
DOI：
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
P. Basser
中科院分区：
文献类型：
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作者：
V. Pickalov;P. Basser
The measurement of the 3-D "average propagator", P(r) from diffusion-weighted (DW) NMR or MRI data has been a "holy grail" in materials science and biomedicine, as P(r) provides detailed microstructural information, particularly about restriction, without assuming an underlying diffusion model. While Callaghan proposed a 3-D Fourier transform relationship between P(r) and the DW signal attenuation, E(q), using it to measure P(r) from E(q) data is not currently feasible biologically or clinically, owing to the staggering amount of DW data required. To address this problem, we propose that computed tomography principles can be applied to reconstruct P(r) from DW signals. Moreover, this reconstruction can be performed efficiently using many fewer DW E(q) data as compared to conventional 3-D q-space MRI or diffusion spectrum imaging (DSI) by employing a priori information about E(q) and P(r)
