Efficacy of family-based treatment for adolescents with eating disorders: A systematic review and meta-analysis
Efficacy of family-based treatment for adolescents with eating disorders: A systematic review and meta-analysis
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DOI：
10.1002/eat.22042
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发表时间：
2013-01-01
影响因子：
5.5
通讯作者：
Szatmari, Peter
中科院分区：
文献类型：
--
作者：
Couturier, Jennifer;Kimber, Melissa;Szatmari, Peter
目的：系统回顾和定量评价青少年进食障碍家庭治疗（FBT）与个体治疗的疗效。方法：使用MEDLINE检索词“家庭治疗和神经性厌食症”以及“家庭治疗和神经性贪食症”对文献进行回顾。这产生了12个随机对照试验，涉及青少年饮食失调和家庭治疗，仔细审查了几个纳入标准，包括：分配隐藏，意向治疗分析，评估者盲法，行为家庭治疗与个体治疗的比较，以及青少年年龄组。检索了这些文章的参考文献。只有三项研究符合这些严格的荟萃分析纳入标准。采用随机效应模型和比值比进行荟萃分析，将缓解视为选择的结局。结果如下：当合并到荟萃分析中时，治疗结束数据表明FBT与单独治疗没有显着差异（z = 1.62，p = 0.11）。然而，当分析6至12个月的随访数据时，FBT上级个体治疗（z = 2.94，p < 0.003），异质性不显著（p = 0.59）。讨论内容：虽然在治疗结束时FBT似乎并不上级于个体治疗，但在612个月随访时，对于患有进食障碍的青少年似乎有显著的益处。(C)出版社：Wiley Periodicals，Inc. (Int J Eat Disord 2013）
Objective: To systematically review and quantitatively evaluate the efficacy of Family-Based Treatment (FBT) compared with individual treatment among adolescents with eating disorders. Method: The literature was reviewed using the MEDLINE search terms family therapy AND Anorexia Nervosa, and family therapy AND Bulimia Nervosa. This produced 12 randomized controlled trials involving adolescents with eating disorders and family therapy which were reviewed carefully for several inclusion criteria including: allocation concealment, intent-to-treat analysis, assessor blinding, behavioral family therapy compared with an individual therapy, and adolescent age group. References from these articles were searched. Only three studies met these strict inclusion criteria for meta-analysis. A random effects model and odds ratio was used for meta-analysis, looking at remission as the outcome of choice. Results: When combined in a meta-analysis, end of treatment data indicated that FBT was not significantly different from individual treatment (z = 1.62, p = 0.11). However, when follow-up data from 6 to 12 months were analyzed, FBT was superior to individual treatment (z = 2.94, p < 0.003), and heterogeneity was not significant (p = 0.59). Discussion: Although FBT does not appear to be superior to individual treatment at end of treatment, there appear to be significant benefits at 612 month follow-up for adolescents suffering from eating disorders. (C) 2012 by Wiley Periodicals, Inc. (Int J Eat Disord 2013)