An examination of the time course of training-induced skeletal muscle hypertrophy
An examination of the time course of training-induced skeletal muscle hypertrophy
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DOI：
10.1007/s00421-011-1905-4
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发表时间：
2011-11-01
影响因子：
3
通讯作者：
Kasishke, Paul R., II
中科院分区：
文献类型：
--
作者：
DeFreitas, Jason M.;Beck, Travis W.;Kasishke, Paul R., II
骨骼肌肥大通常被认为是一个缓慢的过程。然而，这在一定程度上是因为肥大的时间进程尚未得到彻底检查。本研究的目的是使用每周测试，以确定一个精确的时间过程中骨骼肌肥大的阻力训练计划。20名健康、久坐的男性进行了8周的高强度阻力训练。在每周的训练中（W1-W8），使用外周定量计算机断层扫描仪评估优势股的整个肌肉横截面积（CSA）。每周还测量等距最大自主收缩（MVC）。仅在两次训练后（W1），平均大腿肌肉CSA比测试前（P1）增加了5.0 cm（2）（3.46%; p < 0.05），并随着每次测试继续增加。肌肉水肿可能影响早期CSA结果。为了调整这种可能性，假设水肿在W1时最高，从W1开始的下一个显著增加是在W3。W 4是MVC相对于P1的第一个显著增加。因此，显著的骨骼肌肥大可能发生在第3-4周左右。总体而言，从预试验到W8，增加了13.9 cm（2）（9.60%）。这些发现表明，训练诱导的骨骼肌肥大可能发生在训练计划的早期。
Skeletal muscle hypertrophy is typically considered to be a slow process. However, this is partly because the time course for hypertrophy has not been thoroughly examined. The purpose of this study was to use weekly testing to determine a precise time course of skeletal muscle hypertrophy during a resistance training program. Twenty-Wve healthy, sedentary men performed 8 weeks of high-intensity resistance training. Whole muscle cross-sectional area (CSA) of the dominant thigh was assessed using a peripheral quantitative computed tomography scanner during each week of training (W1-W8). Isometric maximum voluntary contractions (MVC) were also measured each week. After only two training sessions (W1), the mean thigh muscle CSA increased by 5.0 cm(2) (3.46%; p < 0.05) from the pre-testing (P1) and continued to increase with each testing session. It is possible that muscular edema may have influenced the early CSA results. To adjust for this possibility, with edema assumedly at its highest at W1, the next significant increase from W1 was at W3. W4 was the first significant increase of MVC over P1. Therefore, significant skeletal muscle hypertrophy likely occurred around weeks 3-4. Overall, from the pre-testing to W8, there was an increase of 13.9 cm(2) (9.60%). These findings suggested that training-induced skeletal muscle hypertrophy may occur early in a training program.