New Appearance of Fragmented QRS as a Predictor of Ventricular Arrhythmic Events in Patients With Hypertrophic Cardiomyopathy
New Appearance of Fragmented QRS as a Predictor of Ventricular Arrhythmic Events in Patients With Hypertrophic Cardiomyopathy
复制标题
DOI：
10.1253/circj.cj-19-0968
复制
发表时间：
2020-03-01
影响因子：
3.3
通讯作者：
Ito, Hiroshi
中科院分区：
文献类型：
--
作者：
Ogura, Soichiro;Nakamura, Kazufumi;Ito, Hiroshi
背景资料：12导联心电图QRS波群中的多个尖峰（碎片QRS [fQRS]）与肥厚型心肌病（HCM）患者的心室肌事件（VAE）相关。本研究的目的是评估新出现的fQRS和心脏事件之间的关联与HCM.Methods和结果：基线fQRS和心脏事件，即VAE，心力衰竭相关的住院治疗，和全因死亡之间的关联，回顾性评估146例HCM患者（46例fQRS，100例无fQRS）。中位随访时间为5.3年。29例有基线fQRS的患者和32例无基线fQRS的患者发生了心脏事件（63% vs. 32%; P
Background: Multiple spikes in the QRS complex (fragmented QRS [fQRS]) on 12-lead electrocardiography have been associated with ventricular arrhythmic events (VAEs) in patients with hypertrophic cardiomyopathy (HCM). The aim of this study was to assess the association between new appearances of fQRS and cardiac events in patients with HCM.Methods and Results: The association between baseline fQRS and cardiac events, namely VAEs, heart failure-related hospitalization, and all-cause death, was evaluated retrospectively in 146 HCM patients (46 patients with fQRS, 100 without fQRS). The median follow-up was 5.3 years. Cardiac events occurred in 29 patients with baseline fQRS and 32 patients without baseline fQRS (63% vs. 32%; P