Prevention and treatment of ischemia of the liver.
Prevention and treatment of ischemia of the liver.
复制标题
预防和治疗肝脏缺血。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
P. Hasselgren
中科院分区：
文献类型：
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作者：
P. Hasselgren
已经提出了多种方法来保护肝脏在缺血期间或再灌注后免受损伤。大多数药物是在缺血发生前施用的，但据报道，治疗后对 MP、多巴胺和 ATP-MgCl2 具有有益作用。以前的研究主要是在实验动物身上进行的，但低温和类固醇也被用来保护患者的肝脏免受缺血性损伤。然而，尚无对照临床试验证明任何类型的预防或治疗人类肝脏缺血的功效。
Various modalities have been proposed to protect the liver from injury during the ischemic period or after reperfusion. Most of the drugs were administered before the onset of ischemia, but a beneficial effect of post-treatment was reported for MP, dopamine and ATP-MgCl2. Previous studies were mainly performed upon experimental animals, but hypothermia and steroids were used to protect the liver from ischemic injury in patients as well. However, no controlled clinical trials exist demonstrating the efficacy of any type of prevention or treatment in ischemia of the human liver.